CASE REPORT 1

This case is of an 18 year old male, who fell from a train and remained in a coma for six months. When he visited NeuroGen BSI, he was found to be hypertonic and hyperreflexic , disoriented in time, place and person, had an aggressive behavior, had severe motor weakness in all limbs, had no bowel and bladder control and could not follow simple commands. His MRI showed reduction in the density of the posterior callosal fibers especially on the right side. Gliotic changes in the bilateral anterior temporal, basifrontal, right insular right parietal and right peritrigonal regions and in splenium of corpus callosum with innumerable petechial foci of hemosiderin staining in both cerebral hemispheres represent sequelae of diffuse axonal injury. His PET CT Scan showed reduced metabolic activity in precentral, broca’s, sensory, motor, wernicke’s, Insula, Lateral, Temporal, Caudate and Putamen, Parietal, Cerebellum, Lobulus Quadrilateral, Medial Temporal Lobe. Thereafter he underwent Cell Therapy for Traumatic Brain Injury in India, at NeuroGen Brain and Spine Institute.


Improvements seen in the patient post Cell Therapy for Traumatic Brain Injury in India:

  • His eye contact was improved

  • Through the help of gestures, he was able to indicate his need for water and food

  • He could turn over both his sides independently

  • His perception was improved

  • There has been a major progression in his command following

  • His spasticity had reduced drastically

  • His sitting and standing balance were improved

  • His right hand voluntary control was improved

  • Neck holding improved.

  • His behaviour was more controlled especially in his aggressiveness and understanding

  • His emotional response were improved

  • His drooling habit stopped completely

  • He started using his left hand to eat

  • His FIM score greatly improved from 19 to 30.


The fact that he slowly started regaining his activities after a period of six months was more than what he hoped for.


The father of the patient expressed, “When my son went into a coma for six months, I had given up all hope, says the patient’s mother. Today, we cannot believe that he is the same person that he was, months ago. With successive therapies in cell therapy for traumatic brain injury in India, we noticed that his eye contact has improved drastically. He can turn over on both sides without taking any help. His standing and sitting balance have improved. Within a span of six months, we noticed that all his disabilities improved for the better. At present, we are happy seeing his growth and hopeful for his full growth and development.”

CASE REPORT 2

This case is of a 34 year old man who was diagnosed with a case of a head injury / traumatic brain injury (TBI) due to the fall of a heavy object after which he suffered a subarachnoid hemorrhage and parietal bone fracture. He was operated twice and had a residual right sided hemiparesis. An assessment showed that he was hypertonic and hyperreflexic and had grade 2 spasticity in right upper extremity and grade 1 spasticity in the lower extremity, walks with a circumduction gait, he had slight memory affection, had slurred speech and right sided facial paralysis. His MRI suggested large cystic encephalomalacia or gliosis in left fronto parietal and left superior temporal lobes with marked ex-vacuo dilatation of left lateral ventricle. Wallerian degeneration of left cerebral peduncle and left hemipons. His PET CT Brain reports showed gliosis in left front parietal cortex with areas of severe hypometabolism.


Improvements seen in the patient post Cell Therapy for Traumatic Brain Injury in India


    He underwent cell therapy for traumatic brain injury in India, at NeuroGen Brain and Spine Institute. and after a follow-up of six months showed the following improvements

  • An improvement was seen in his level of confidence while doing regular activities Improvisation in his sitting and standing posture

  • His gait pattern marked a great improvement

  • His spasticity in his right upper extremity was greatly reduced

  • Improvement in his range of motion

  • Improvement in his sensations on right side

  • Improvement in his facial expressions

  • His remote memory and recent memory are also improved

  • His planning, organization, sequencing and decision making skills improved

  • Improvement in his speech and orientation

  • Improvement in his tongue flexibility and speech clarity

  • There was also a reduction in his semantic paraphasias


Apart from the clinical improvement there were also changes in his post SCT PET CT scan which showed better metabolic activity in the left parieto- occipital cortex at the periphery of the gliotic lesion and contributed to his overall improvements.


The patient’s family expressed, “Through cell treatment for traumatic brain injury, we have learnt a lesson ourselves and that is never to lose hope. We are happy and pleased to say that our son’s condition has improved. Because of all these improvements, his confidence level has soared. We have observed that he has become more expressive as his facial movement has become better. Today he has a better sitting and standing posture. There is a marked improvement in all his earlier disabilities and we are really thankful to you all for that.”