high functioning autism

Know What Is ‘High Functioning Autism’, And How Does It Manifest in Children with Autism?

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Autism is a complex neurodevelopmental condition that is perceptible during the first three years of age. A child with autism finds it difficult to decipher straightforward things like comprehending, perception, problem solving, speech, antisocial behaviour and social interaction. This slows down their normal development and functioning significantly making them dependent on their caretakers.

High Functioning Autism is term given to people with autism who are considered to be cognitively “higher functioning” (with an IQ of 70 or greater), than other children suffering from this disorder.

Some signs of High Functioning Autism:

  • Delayed initial speech, but functional communication as child ages
  • Difficulty in social interaction – unable to relate to peers
  • Obsessive behaviour over appearance, hygiene, fears and social affairs
  • Sensitivity to emotions
  • Susceptible to outbursts or meltdowns when too tired or overly prompted
  • Oral, vestibular, proprioceptive, tactile, auditory and visual sensory issues
  • Lack of comfort in social situations – seeming ‘grown up’ for their age. Not being able to understand jokes, sarcasm, humor, or usual shenanigans among peers


sensory issues in children with autism

Understanding the Sensory Issues in Children with Autism

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Sensory integration is a neurobiological process in which the sensory information from the environment is interpreted and integrated by the brain. In the brains of people with autism, this process may not always be carried out appropriately, leading to a number of problems.

Let us try to understand one of the major challenges faced by children with autism. The symptoms of autism include social and communication impairments, repetitive and restrictive behaviour and difficulty in processing sensory information. Individuals with autism often have difficulty regulating and responding to sensory inputs from the environment as well as the sensations from their own bodies.

The sensory systems can be broken down into six areas. These can be divided into two main areas hyper (high) and hypo (low) sensitivity. However, it is important to remember that the difficulties/differences may for some individuals fall into both areas. Proprioceptive system tells us Situated in the muscles and joints, this tells us where our bodies are. It also informs us where our body parts are and how they are moving. Visual system Situated in the retina of the eye and activated by light, our sight helps us to define objects, people, colours, contrast and spatial boundaries. Smell olfactory tells us by chemical receptors in the nose, process smells in our immediate environment. However, Smell is a sense taken for granted and is often neglected or forgotten about. It is, however, the first sense we rely upon hearing situated in the inner ear, this informs us about sounds in the environment. It is the most commonly recognised aspect of sensory impairment.touch tells us Situated on the skin, the body’s largest organ, this relates to touch, type of pressure and level of pain and helps us distinguish temperature (hot and cold).vestibular system tells us Situated in the inner ear, this provides us with information on where our body is in space and its speed, direction and movement, all in relation to the pull of gravity. It is fundamental in helping us to keep our balance and posture.taste tells us Processed through chemical receptors in the tongue, this tells us about different tastes – sweet, sour, bitter, salty and spicy. Individuals will often have restricted diets as a result of their taste buds being extra sensitive.

These problems can manifest in a number of ways. A child with autism may:

  • Be over-responsive or under-responsive to any sensory input.
  • Have either an activity level that is too high or too low.
  • Be in motion constantly or tire easily.
  • Have fine motor coordination issues.
  • Have difficulty adjusting to new situations.

This information is important for to know so that we can increase our level of understanding and awareness about autism.


Autism Stem Cell Treatment

Understanding Autism Stem Cell Treatment

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Autism is a range of disorders which are characterized by several challenges in social skills, communication skills, repetitive behaviors, emotional imbalances and overall cognitive skills development. These developmental deficiencies are seen within the first three years of the child’s growth. These disrupt their normal functioning making them dependent on others for their basic requirements. Autism cannot be reversed but with proper early interventions, these children can be brought up to be independent and lead a better quality life.

Some of the signs and symptoms of Autism are difficulty in verbal and non-verbal communication, difficulty in making friends and building relationships, slow or impaired development of spoken languages, over sensitivity to loud noises, short attention span and more.

The causes of Autism have been a topic of debate for a long time. However, there is no consensus on the specific causes of autism. The most popular belief is that a structural or functional damage to the nervous system can lead to autism spectrum disorder.Gene mutation is one of the possibilities for the deficient brain development leading to autistic features. Non-genetic factors such as prenatal complications, the presence of meconium in the amniotic fluid, insufficient nutrient uptake during pregnancy etc can also be the cause of Autism. Environmental factors such mercury poisoning, maternal stress and exposure to strong medications, toxins, infections or radiations may also be responsible for autism.
The use of Stem Cell Therapy for the treatment of Autism is bringing new hopes to the patients and the doctors as well. Oxygen deprivation and immune dysregulation are few of the main causes which may lead to autism. These factors are directly linked with the slow functioning of the brain.

Autism Stem Cell Treatment

Regenerative therapy using stem cells is being thoroughly researched to use it as the prospective therapy for children on the spectrum. The understanding is that the stem cells have the capacity to differentiate into different cells and structure specialized cells from the mother cell. These cells can help repair the affected neural tissue at the molecular, structural and functional level. It is able to regulate cell differentiation, tissue and organ repair and anti-inflammatory actions.

At NeuroGen BSI we have successfully used Autism stem cell treatment with excellent results. Patients have shown overall improvements in speech, social interactions, eye contact, reduced aggressive behaviour and improvement in non-verbal communication skills. PET-CT scans of the patients have shown improvements in the brain metabolism which can be related to enhanced functional abilities.

Muscular Dystrophy Stem Cell Treatment

Understanding Muscular Dystrophy Stem Cell Treatment

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The earliest cases of muscular dystrophy were detected in 1830 when a study was conducted on young boys on the progressive weakening of their muscles. This was done by Sir Charles Bell and it was understood that about 30 genetic disorders were responsible for the alarming rate of muscle weakening that applied to all voluntary movements.

The symptoms of muscular dystrophy worsen with time as the muscles deteriorate continually and start to weaken. There are nine types of muscular dystrophy. This set of genetically affected disorders share some pathological characteristics but differs in the age of onset, rate at which it progresses, distribution of weakness, severity, inheritance pattern and molecular defect.

Muscular Dystrophy Stem Cell Treatment

Several studies are being conducted on the possibilities of stem cell regeneration and repair of the damaged muscles cells. Stem cells are those types of cells that develop at the early growth stage and have the capability to convert into any type of body cells and undergo self regeneration. The adult muscles are able to undergo renewal and regeneration due to the presence of distinctive subpopulation of muscle cells known as satellite cells.These cells are chiefly associated with skeletal muscle regeneration. For Muscular Dystrophy Stem Cell Treatment is considered a great option as in order to treat this disorder there is a need for progressive muscle proteins and restoration of the stem cell pool.

The mechanism which is involved in stem cell treatment for muscular dystrophy is cell infusion, secretion of cytokines, increased oxygen supply and vascularization in the damaged area. These mechanisms act together to prevent cell death, decrease symptoms and restore damaged tissues.

Other Treatments for Muscular Dystrophy

Muscular dystrophy is one of the most complicated disorders and although its symptoms are well understood its treatment is elusive. The most conventional method is the use of drugs which helps to combat muscle dystrophy. Gene therapy is an advanced therapy wherein the defective or damaged gene is replaced with the normal gene.

At NeuroGen BSI over 1000 patients have been treated with stem cell therapy for muscular dystrophy. After successful completion of the therapy patients have shown remarkable improvement in trunk muscle strength, limb strength on manual muscle testing and balance, ambulation, hand function, increase in stamina and better trunk balance.

Risks of ASD in A Sibling to Your Child/Children with Autism

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Modern families, in recent times, are aware of autism and its related disorders. Most of them have a well maintained family tree that offers a defined family history.

When evaluating a child for autism, it is important to know about the family history and search for any genetic disorder that may have been in the family. Parents’ perception of autism has seen a considerable change that has, in turn, made them mature. They may consult the possibility, with counsellors, of their second child inheriting the same syndrome as its older sibling with autism.

In the past, parents may have been reluctant, but now their thoughts have changed remarkably.

Every parent while planning a sibling for their child/children with autism often have a query, “what is the threat of planning another child?” It is highly suggested that the parents must consult with a genetic counsellor and for early intervention for the unborn child having sibling with autism. A study has shown that:

  • If a family has one child with autism, there is a 15 % chance that the next child may also have ASD.
  • If the next child happens to be a male, then the risk is 2-3 times more than for girls.

Younger siblings, of children with autism spectrum disorder, are more likely to have ASD syndromes like language delays, learning difficulties, lack of social communication, repetitive behaviour and sensory sensitivities.

It is believed that autism is the effect of multiple genes interacting with each other. These genes are the root cause that develop a baby’s brain abnormally or make him/her vulnerable to other unknown neurological factors. There may also be a combination of genetic and environmental influences too, that may affect normal development.

If the child is born without any influence of ASD, there may be a possibility (negative) of intellectual ability, behaviour of the older sibling with autism to impact a healthy relationship between the two siblings. There is also a possibility (positive) of a sense of responsibility for the sibling with autism by the younger healthy sibling. Many of the siblings of children with autism function well with their younger siblings in adolescent and adult stages.

It is advisable for parents to gain more information on autism and the risk in welcoming a second child in the family that already has a child with autism. Modern families who want to have a child are very mindful of their family history.

So, YES, Things Have Changed!

Dementia, signs of dementia, signs and symptoms of dementia, symptoms of dementia, causes of dementia, treatments for dementia

Dementia – Signs, Symptoms, Causes and Treatments

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Dementia is not a disease but a disorder that leads to a severe deterioration of mental capabilities of an individual, resulting in the slowing down of the cognitive and socializing capabilities. It can be largely defined as a group of symptoms that erupt due to related brain disorders. Memory loss is the most common symptom of dementia. However, not all cases of memory loss can be related to dementia. Dementia occurs when multiple functions of the brain are affected where some sense of memory, reasoning, language, judgment and others are not entirely lost.

Symptoms and Causes of Dementia

Complex and restrictive brain functioning of cognitive skills such as emotional behavior, language, memory, perception, thinking and judgment is a symptom of dementia. Other symptoms include memory loss, difficulty in performing complex tasks, planning and organizing, difficulty in communication and other motor functions. Unexpected changes in personality such as inappropriate behavior, paranoia, hallucinations, agitation, orientation problems which results in getting lost and inability to reason.

Damage to brain cells are the main reason for dementia. Correspondence between brain cells are inhibited due to the injury. This prevents the brain to maintain normal cognitive and behavioral interactions. Dementia is of many different types depending on causes and effects.

Medicinal Treatment for Dementia

Alzheimer’s, which is a form of progressive dementia, does not have any form of cure or treatment to stop it from progressing further. However, there are medical treatments that can improve on the symptoms momentarily. Drugs in the category of cholinesterase inhibitors are presently being used to decrease the effects of the symptoms. Non-drug therapies such as physical therapy and occupational therapy are also being used to help patients deal with behavioural changes and daily activities.

Dementia Stem Cell Treatment

Stem cell therapy has the ability to renew and generate new cells which can repair the damage done to the brain cells. This can result in restoration of the lost brain cells offering an option for the treatment of dementia. It has been proved that in Dementia stem cell treatment the cells obtained from the bone marrow can help support the development of new nerve cells as well as making a conducive environment for the new cells to thrive. These cells also work together to improve the reasoning, thinking and memory abilities of patients suffering from dementia through neuro protection, angiogenesis and metabolic activities. The treatment uses Neuro-Rehabilitation and Autologous Hematopoietic Stem Cell Transplantation which can help delay the progression of dementia.

stem cell therapy for spinal cord injury, spinal cord injury treatments

Stem Cell Treatment for Spinal Cord Injury in Mumbai

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Any kind of injury calls for immediate medical attention and complete care. Ignoring an injury only worsens the situation over time and becomes bigger, more painful and a hindrance to normal life.


The Spinal Cord is the critical connection between the brain and the vertebral canal via nerve tissues. An injury to the spinal cord, either traumatic or non-traumatic, can lead to severe damages to body functions and requires effective spinal cord injury treatment. Any sort of damage to any spinal nerve leads to a spinal cord injury. The more severe the damage, more greatly will the body functions be affected. Depending on the severity of the spinal cord injury a person may show certain symptoms, including:


  • Difficulty in walking and body movement
  • Difficulty in differentiating sensations
  • Poor control over bowel or bladder movements
  • Numbness/Tingling feeling
  • Breathing problems


A spinal cord injury encompasses any damage to the vertebrae, ligaments or disks of the spinal column. Traumatic spinal cord injury may occur in case of motor vehicle accidents, sports related, violence or falls. Whereas, non-traumatic injury may occur as a result of arthritis, cancer, infections, inflammation or disk deterioration.


Spinal Cord Injury Treatment


Whether traumatic or non-traumatic, severe or a low level injury, immediate medical help must be sought to understand the most effective spinal cord injury treatment. There are several conventional spinal cord injury treatment options like surgery, rehabilitation sessions, pain management, physical therapies, counselling, use of assisted devices etc. Injury to the spinal nerve tissues is often permanent as the regenerative process of the spinal cord and the brain are not capable enough to repair and renew immediately.


Stem cell therapy is the latest breakthrough and touted to be the most effective spinal cord injury treatment, at present. If an injured person is treated within 6 months it lowers the risk of inflammation and thus can be managed better. Stem cell therapy supports and facilitates neuro-protection and neuro-regeneration that helps in the growth of new and healthy neurons. It fastens the repair and renewal process, thus leading to faster treatment.


NeuroGen Brain and Spine Institute has helped many people get back to normal life and healthy bodily functions through effective spinal cord injury treatments. We offer complete care and the best of treatment options, after carefully understanding individual needs. Stem cell therapy as a spinal cord injury treatment has proven to be safe, effective and currently the best treatment option.

causes of mental retardation, mental retardation treatment

The Causes of Mental Retardation and Its Treatment Using Stem Cell Therapy

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Mental Retardation is a disability that appears particularly in children and teenagers. A developmental disorder characterized by the intelligence quotient being well below average. A mentally retarded patient shows signs of below average intellect and performance and faces obstacles in almost every activity from communication, self-care, sense of direction, safety, reasoning to social skills and academic performance.

Everything takes a backseat. By the existing classification system, Mental retardation can be classified broadly into four tiers, namely

  • Mild Mental Retardation- Characterized by an IQ range of 50-69, they are unable to deal with responsibilities and socially immature but can benefit from specialized education plans and are fully independent in self-care.
  • Moderate Mental Retardation- With an IQ range of 35-49 they are unable to live independently but are slow learners with limited capacity in communication and comprehension of language.
  • Severe Mental Retardation- An IQ range of 20-34, characterized by significant motor impairment and abnormal or damaged CNS (Central Nervous System).
  • Profound Mental Retardation- An IQ below 20. In need of constant help and supervision, such patients cannot care for their own needs and resort to very basic non-verbal communication.

NeuroGen Brain and Spine Institute has expertise in treating neurological disorders with quality personnel and doctors required and ready to tackle every obstacle in Mental Retardation Treatment with the help of Stem Cell Therapy.

Symptoms and Causes of Mental Retardation

Some of the symptoms that are associated with poor mental growth are issues with problem-solving, reasoning, poor memory, ability to control emotions and decreased concentration power all of which are caused by conditions that are detrimental to brain-development and harm the brain before or after birth or in the early years of one’s life. Some of these include:

  • Genetic anomalies.
  • Trauma before or during parturition.
  • Environmental poisoning.
  • Poisoning due to Intrauterine exposure to Amphetamines, LSD or other such drugs.

Stem Cell Therapy For Mental Retardation

The conventional approach to the treatment of Mental retardation includes various treatment options to improve a patient’s mental ability and to gradually ease them into normal social life. However, mental retardation treatment through Stem Cell Therapy at NeuroGen BSI is one of the most effective ones, and it is aimed at rebuilding and healing the nervous tissues. Properties of self-renewal and differentiation of stem cells are being triggered and used.

These practices are showing great promise in the field of mental retardation management including internal repair processes, reduction in inflammation and activation of nearby stem cells.

symptoms of muscular dystrophy

Symptoms of Muscular Dystrophy and Its Treatment via Stem Cell Therapy

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Detection of muscular dystrophy started to surface in the early years of the 19th Century. Dystrophy originates from the Greek word ‘dys’, which means, ‘to nourish.’ 1 male in every 3500 is found suffering from this horrendous disease.

Muscular dystrophies are a set of genetic diseases that are characterized by weakness and eventual or progressive degeneration of muscles. There are approximately a set of around 30 such genetic diseases that can lead to an alarming decrease in the strength of skeletal muscles. It worsens in due time as the muscles continuously deteriorate.

To address a disease as mentally and physically taxing as the various kinds of Muscular dystrophies (MD), expert and foolproof guidance is of prime importance. NeuroGen Brain and Spine Institute has been set up to assist patients all over the world with incurable neurological disorders such as Cerebral palsy, autism, stroke, muscular dystrophy, etc.

Along with drug treatment and rehabilitation, it also offers Muscular dystrophy stem cell treatment which has been proven to be potential not only in stabilizing the symptoms of MD but also in putting brakes on the rapid pace of progression of the disease.

Types and causes of Muscular dystrophy

This collection of genetic disorders is usually similar in clinical characteristics and features; but they differ mainly in their intensity, level of weakness, distribution, and pace of progression and age of occurrence. Duchene, Becker and Emery-Dreifuss MDs usually occur at an early age ranging from infants in the first kind to teens and young adults in the remaining two types. Myotonic (MD) affects middle aged individuals whereas Distal MD and Oculopharyngeal MD appear after the onset of the fourth decade of human life.

A cluster of disorders which disrupt one of the tons of genes that code proteins for muscle integrity give rise to Muscular dystrophy. Thus, the cells maintaining the muscles consequently degenerate leading to muscle weakness. Muscular dystrophy is hereditary and can be transmitted as

  • Autosomal Dominant
  • Autosomal Recessive
  • X-linked inheritance or when the mother carries the faulty gene.

How can stem cell therapy be helpful?

The entire mechanism of muscular dystrophy stem cell treatment is based on tissue remodeling and prevention of cell death. Stem cells have the capacity to convert any kind of cells and undergo self-regeneration. The ability of the adult muscle to undergo renewal is due to satellite muscle cells, an integral part of skeletal muscle regeneration. At NeuroGen BSI Stem cell therapy is paving the way for revolutionary treatment of MD to restore the stem pool.

Presently, the institute boasts of over ninety-percent of its patients showing tremendous promise in the development of muscle strength and balance who have undergone this treatment. Without any doubt, the signs of a very bright and prosperous future are here.

stem cell stroke treatment

How Can Stem Cell Treatment Treat Stroke?

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Like we know, blockage of blood supply and blood vessel within the brain leads to the occurrence of stroke. Known for its added complications, stroke is an anomaly that one always tends to avoid for the better. A person suffering from stroke or attack must be immediately treated to avoid critical medical conditions.

If treated timely, future complications can be averted. NeuroGen Brain and Spine Institute is such medical institute that aims to treat a wide range of diseases from stroke to muscular dystrophy through stem cell treatment; With the help of this medical institute, Stem cell stroke treatment in Mumbai has taken a huge leap forward along with the rest of India.

Symptoms of Stroke:

  • Loss of balance during movement.
  • Loss of vision or dimming in one or both eyes.
  • Severe headaches.
  • Loss of speech and ability of comprehension of surroundings.

Causes and Conventional Treatment

Strokes can be of various kinds demanding different kinds of treatment. Ischemic stroke is due to the obstruction of blood clots to the blood flow in the brain. Transient ischemic stroke is also a type which is known as mini stroke. It occurs due to a temporary reduction in blood supply to the brain whereas hemorrhagic stroke originates from a damaged blood vessel which bleeds into the brain. It constricts the region of brain tissue and can lead to high blood pressure.

Stem Cell Therapy For Stroke Treatment

Stem cell therapy is a kind of treatment where stem cells are used to cure the issue of stroke. For stroke therapy, the application of stem cells has been influential in instilling hope. These stem cells can help cure stroke without extensive operations. Stem cell therapy also restores the functions of the brain especially after the stroke and helps in repair and regeneration of damaged tissue.

Stem cell stroke treatment in Mumbai has received a massive boost after the advent of NeuroGen BSI in Mumbai. They have successfully treated over a hundred patients with the utmost dedication and commitment to bring improvements in their living conditions.

Research has shown that with stem cell therapy, one-third of the patients showed moderate improvements and half of them had shown signs of major improvements and not only functional changes. Without any doubt, stem cell therapy for stroke victims promises a better and safer future.